Your binder or CAR
Evaluate SafeCAR architecture with your antigen-binding domain.
Platform 1Cell Therapy Toolbox
Delivery.Safety.Persistence.
Three technologies. License one or combine them for your cell-therapy program.
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Three technologies
Delivery. Safety. Persistence.
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Delivery
Reach T cells and NK cells.
Limit exposure elsewhere.
Delivery vectors designed to maximize T-cell or NK-cell selectivity and limit off-target liver and kidney exposure.
License a delivery vector for your cell type and payload.
In vivo cell engineering
Build on your program
Keep your target.
Add the capability you need.
Configure SafeCAR
Your CAR, TCR or other payload
Co-encode PyroTIMER to deliver a secreted TGF-β trap with your therapeutic cells.
Your in vivo T-cell or NK-cell program
Pair your therapeutic payload with a cell-selective delivery vector.
SafeCAR and PyroTIMER are available independently for in vivo or ex vivo programs.
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